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Immune checkpoint inhibitors have revolutionized cancer treatment by enhancing anti-tumor immune responses.However, their impact on fertility is an emerging concern, particularly among young patients, including children.This review aims to assess the effects of immune checkpoint inhibitors on reproductive angry beavers shirt health and fertility pr
Filamins are important actin cross-linking proteins implicated in scaffolding, membrane stabilization and signal transduction, through interaction with ion channels, receptors and signaling proteins.Here we report the physical and functional interaction between filamins and polycystin-2, a TRP-type cation channel mutated in 10-15% patients with aut
Migrating eastern North American monarch butterflies use a time-compensated sun compass to ovation toddler helmet adjust their flight to the southwest direction.Although the antennal genetic circadian clock and the azimuth of the sun are instrumental for proper function of the compass, it is unclear how these signals are represented on a neuronal l
We have previously shown that plasma high density lipoproteins (HDL) stimulate release of prostacyclin, measured as its stable metabolite, 6-keto-PGF1 alpha, by cultured porcine aortic endothelial cells.The present experiments were designed to elucidate the contribution of HDL lipids to endothelial cellular phospholipid pools and to prostacyclin sy